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Sequence Colorado

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SequenceMedicine Regional Network

Sequence Colorado

Precision medicine at altitude

Colorado's healthcare ecosystem is built on innovation. From the Anschutz Medical Campus to the growing Front Range biotech corridor, the state is positioned to lead the integration of genomic medicine into value-based care delivery.

5.8M
Residents Served
64
Rural Counties
53%
Avg Diagnostic Yield
Regional Strengths

Colorado's Genomic Landscape

A convergence of world-class pediatric medicine, academic research power, and a life sciences ecosystem primed for genomic integration.

Children's Hospital Colorado

Ranked among the nation's top pediatric centers, with a Level IV NICU where rapid genomic sequencing delivers diagnostic yields of 34–59%. Every critically ill neonate deserves a molecular answer within their admission.

Anschutz Medical Campus

One of the largest academic health science campuses in the nation, housing the University of Colorado School of Medicine. A research and clinical hub generating the evidence base that CarePathways translate into practice.

Front Range Biotech Corridor

Colorado's life sciences sector is growing rapidly along the Front Range, attracting genomics companies, diagnostic laboratories, and bioinformatics talent that form the operational backbone of precision medicine delivery.

Rural Health Challenge

With 64 counties classified as rural or frontier, Colorado's geography creates a significant access gap for specialty genomic services. Telegenetics and structured CarePathways can bridge this divide systematically.

Structured Delivery

CarePathways for Colorado

Evidence-based, bundled care episodes designed for Colorado's patient population, provider landscape, and payer environment. Each pathway turns a diagnostic question into a measurable, cost-effective care episode.

Pathway 01

Pediatric & NICU Genomics

Rapid whole-genome and exome sequencing for critically ill neonates and children at Children's Hospital Colorado. Diagnosis within the admission eliminates the diagnostic odyssey before it begins and reduces NICU length of stay by up to 25%.

34–59% diagnostic yield
Rapid WGS NICU/PICU 3-day TAT LOS Reduction
Pathway 02

Rare Disease Diagnosis

Structured exome and genome sequencing for undiagnosed patients cycling through Colorado's health system. Targeting the 5–7 year diagnostic odyssey that generates $50,000–$500,000+ in unnecessary care per patient, with telegenetics bridging access for rural communities.

~53% average diagnostic yield
ES/GS Telegenetics 20 Organ Systems Rural Access
Pathway 03

Pulmonary Genetics

Colorado's altitude creates a unique clinical context for pulmonary genetic conditions. Primary ciliary dyskinesia, hereditary pulmonary arterial hypertension, and pulmonary fibrosis present with distinct phenotypic profiles at elevation, making early molecular diagnosis critical.

47–80% diagnostic yield
PCD PAH Pulmonary Fibrosis Altitude Context
Pathway 04

Precision Oncology

Comprehensive genomic profiling integrated into Colorado's cancer care networks. Tumor-normal sequencing, germline risk assessment, and pharmacogenomic optimization ensure that every oncology patient receives targeted, evidence-driven therapy from the start.

Actionable in 60%+ of cases
Tumor-Normal Germline PGx Targeted Therapy
Statewide Access

Bridging Urban and Rural

Genomic medicine should not require a drive to Denver. Structured telegenetics pathways extend the reach of Colorado's academic centers to every corner of the state.

From the Front Range to the Western Slope

Colorado's rural and frontier communities face a compounded version of the rare disease challenge: the same diagnostic odyssey that wastes years and resources in urban settings becomes even longer when the nearest geneticist is a four-hour drive away.

CarePathways solve this by embedding telegenetics consultation, remote sample collection, and digital result delivery into a single structured care episode. The patient stays in their community. The expertise comes to them.

  • Telegenetics pre-test counseling eliminates travel barriers for rural families
  • Remote sample collection through local healthcare facilities and mail-in kits
  • Digital result disclosure with genetic counselor follow-up via secure video
  • Integration with UCHealth and regional hospital networks for coordinated care
  • Cascade testing for family members across geographically dispersed households
Denver / Aurora
Academic Hub
Colorado Springs
Regional Center
Telegenetics Network
Western Slope
Rural Access Point
San Luis Valley
Rural Access Point